If needed, babies can be monitored for symptoms.ĭoes taking duloxetine in pregnancy affect future behavior or learning for the child? Let your healthcare providers know before delivery if you are taking duloxetine. In rare cases, some babies may need to stay in a special care nursery for a few days until these symptoms go away. Not all babies exposed to duloxetine will have symptoms. Most of the time the symptoms are mild and go away on their own, usually within a few weeks. Symptoms might include breathing problems, jitteriness / tremors, more or less muscle tone, irritability, problems sleeping, and a hard time eating or regulating their body temperature. These symptoms are sometimes referred to as withdrawal. The use of duloxetine during pregnancy can cause temporary symptoms in newborns soon after birth. Will it cause withdrawal symptoms in my baby after birth?
I need to take duloxetine throughout my entire pregnancy. For more information, please see our fact sheet on depression at. This makes it hard to know if it is the medication, depression, or other factors that can increase the chance for these problems. However, research has also shown that when depression is left untreated during pregnancy, there could be an increased chance for pregnancy complications. Some studies suggest that taking duloxetine throughout pregnancy may increase the chance for pregnancy complications such as high blood pressure disorders and heavy bleeding after birth. Based on the studies reviewed, taking duloxetine in pregnancy is not expected to increase the chance of birth defects above the background risk.ĭoes taking duloxetine in pregnancy increase the chance of other pregnancy-related problems? As there can be many causes of miscarriage, including depression itself, it is hard to know if a medication, underlying condition, or other factors are the cause of a miscarriage.ĭoes taking duloxetine increase the chance of birth defects?Įvery pregnancy starts out with a 3-5% chance of having a birth defect. Other studies have not reported an increased chance. Two studies reported taking duloxetine could slightly increase the chance of miscarriage. Based on the studies reviewed, it is not known if taking duloxetine increases the chance for miscarriage Miscarriage is common and can occur in any pregnancy for many different reasons. It is not known if duloxetine can make it harder to get pregnant.ĭoes taking duloxetine increase the chance for miscarriage? Can it make it harder for me to get pregnant? In healthy adults, it takes up to 3 days, on average, for most of the duloxetine to be gone from the body. People eliminate medication at different rates. I am taking duloxetine, but I would like to stop taking it before getting pregnant. It is not known how withdrawal may affect a pregnancy. Stopping this medication suddenly can cause some people to have withdrawal symptoms. If you plan to stop this medication, your healthcare provider may suggest that you slowly lower the dose instead of stopping all at once.
Some people may have a return of their symptoms (relapse) if they stop this medication during pregnancy. Your healthcare providers can talk with you about the benefits of treating your condition and the risks of untreated illness during pregnancy. However, it is important to talk with your healthcare providers before making any changes to how you take this medication. Sometimes when people find out they are pregnant, they think about changing how they take their medication, or stopping their medication altogether. It is sold under brand names such as Cymbalta® and Irenka®. Duloxetine belongs to a group of medications known as serotonin-norepinephrine reuptake inhibitors (SNRIs). This information should not take the place of medical care and advice from your healthcare provider.ĭuloxetine is a medication that has been used to treat depression, anxiety, and chronic pain.
This sheet is about exposure to duloxetine in pregnancy and while breastfeeding.
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